1-(3-Hydroxymethylpyridin-2-yl)-4-methyl-2-phenylpiperazine CAS 61337-89-1

1-(3-Hydroxymethylpyridin-2-yl)-4-methyl-2-phenylpiperazine CAS 61337-89-1 suma

Zvenyama
Chitarisiko: Mumamiriro ezvinhu akajairika, inogona kunge yakasimba crystalline, asi iyo chaiyo crystal morphology, ruvara uye zvimwe zvinhu zvinofanirwa kusanganiswa neakawanda nyanzvi yekuona maikorosikopu uye zvinyorwa zvinyorwa kuti zvitsanangure nemazvo. Kuonekwa kwechinhu chakasimba kunotarisa kuti inoshanda sei panguva yekuchengetedza, kutakura uye kuwana, somuenzaniso, crystalline solids inonyanya kukodzera kushandiswa ne spatula.
Solubility: Muzvakajairwa organic solvents, senge ethanol uye methylene chloride, inogona kuratidza madhigirii akasiyana ekunyungudika. Iyo solubility data mu organic solvents yakakosha zvikuru kune organic synthesis kuyedza uchiishandisa seyakagadzirwa kana yepakati, kuitira kuti masayendisiti akwanise kuongorora akakodzera maitiro ekunyungudutsa masisitimu kuti ave nechokwadi chekuti maitiro anoitwa zvakafanana uye nemazvo.

Synthesis nzira
Pyridine uye piperazine zvinobva kune zvinonyanya kushandiswa sezvinhu zvekutanga, uye classical organic reactions senge nucleophilic substitution uye condensation inoshandiswa kugadzira mamorekuru masisitimu. Semuyenzaniso, pyridine derivatives neakakodzera kuchengetedzwa kweboka rinotanga kupinda nucleophilic substitution reaction ne activated piperazine precursors pasi pemamiriro ealkaline kuti aumbe makiyi epakati; Zvadaro, mushure mekusarudzwa kwekudzivirira uye hydroxymethylation matanho, chinangwa chigadzirwa chinogona kuwanikwa. Iyo yese synthesis maitiro inoda kudzora kwakasimba kwekuita tembiricha, kuita nguva uye reshiyo yezvinhu, uye kutsauka kudiki kunoburitsa tsvina, inokanganisa kuchena uye goho rechigadzirwa.

use
Pharmaceutical R & D: Yayo yakasiyana-siyana ye molecular chimiro inobatanidza mapoka anoshanda akadai sepyridine uye piperazine, anoratidza maitiro ekuva inogona kutungamirira mishonga yemishonga. Aya mapoka anogona kudyidzana zvakanangana nemapuroteni akananga, senge mamwe ma neurotransmitter receptors, mune zvipenyu, achipa zvinyorwa zvimiro zvematemplate ekugadzirwa kwemishonga mitsva yekurapa zvirwere zvetsinga uye zvirwere zvepfungwa. Vatsvagiri vanozogadzirisa chimiro chayo uye kuyedza chiitiko chayo kuti varambe vachiongorora kugona kwayo kwemushonga.
Organic Kuvaka Zvivharo: Mune iyo yakazara synthesis yeakaomesesa organic mamorekuru, ibwe remhando yepamusoro rekuvaka. Makemikari anogona kushandisa nzvimbo dzawo dzinoshanda kubatanidza mapoka akasiyana anoshanda kuti awedzere mamorekuru kabhoni maketani uye kuvaka akawanda-mhete masisitimu, achivhura mazano ekubatanidza uye nzvimbo yekushanda yekugadzira organic komisheni ine novel zvimiro uye yakasarudzika mabasa.