2,4,5-Trifluorophenylacetic Acid (CAS# 209995-38-0)
Application
2,4, 5-trifluorophenylacetic acid isimbi chena inoshandiswa kugadzira mushonga mutsva wesitagliptin wepakati pakurapa chirwere cheshuga cherudzi rwechipiri. sitagliptin ndiyo yekutanga DPP-IV inhibitor ichangobva kunyorwa naMerck. Iyo ine yakanaka yekurapa mhedzisiro, diki mhedzisiro, chengetedzo yakanaka uye kushivirira mukurapa kwerudzi rwechipiri chirwere cheshuga, uye ine tarisiro yakakura yemusika.
Tsanangudzo
Chitarisiko Crystallization
Ruvara Ruchena kusvika Kuchena-Kuchena
pKa 3.78±0.10(Zvakafanotaurwa)
Storage Condition Yakavharwa mune yakaoma, Kamuri Tembiricha
Refractive Index 1.488
Safety
Hazard Symbols Xi - Irritant
Irritant
Risk Codes R37/38 - Inogumbura kune yekufema system uye ganda.
R41 - Ngozi yekukuvara kwakakomba kwemaziso
Tsanangudzo Yekuchengetedza S26 - Kana wasangana nemaziso, sukurudza nekukurumidza nemvura yakawanda uye tsvaga mazano ekurapwa.
S39 - Pfeka dziviriro yeziso / kumeso.
WGK Germany 3
HS Code 29163990
Hazard Kirasi IRRITANT
Kurongedza & Kuchengeta
Yakarongedzwa mumadhiramu 25kg/50kg. Ramba uri munzvimbo ine rima, Yakavharwa pakaoma, Kamuri Tembiricha
Nhanganyaya
Kuunza 2,4,5-Trifluorophenylacetic Acid, chena yakasimba iyo inoshandiswa zvakanyanya muindasitiri yemishonga yekugadzira sitagliptin yepakati yekurapa chirwere cheshuga chechipiri.
Sechikamu chakakosha mukugadzirwa kwesitagliptin, 2,4,5-Trifluorophenylacetic Acid yakaita basa rakakosha mukugadzirwa kwemushonga uyu unoshanda zvakanyanya. Sitagliptin ndiyo yazvino DPP-IV inhibitor ichangobva kunyorwa naMerck. Iyo inozvirumbidza yeakanakisa kurapa mhedzisiro, mishoma mhedzisiro, chengetedzo uye kushivirira, uye yave yekuenda-kune mushonga mukurapwa kwechirwere cheshuga chechipiri.
Imwe yemabhenefiti akakosha e2,4,5-Trifluorophenylacetic Acid ndeyekuti inogonesa kugadzirwa kwesitagliptin nemutengo wakaderera, zvichiita kuti vanhu vazhinji vakwanise kuwana mushonga uyu unoshandura hupenyu. Mukuwedzera, inoshanda zvikuru mukurapa chirwere cheshuga uye inopa tariro itsva kune avo vari kurwisana nemamiriro acho ezvinhu.
Kuonekwa kwe2,4,5-Trifluorophenylacetic Acid ikiristalline chena kusvika kunze-chena hupfu, zvichiita kuti zvive nyore kuziva, kubata, uye kutakura. Iyo zvakare yakagadzikana zvishoma pasi pemamiriro akajairika, izvo zvinoreva kuti inogona kuchengetwa kwenguva yakareba pasina kushatisa.
2,4,5-Trifluorophenylacetic Acid ine zvakawanda zvakasiyana-siyana uye inogona kushandiswa mukugadzirwa kwemamwe macompounds akaoma kupfuura sitagliptin intermediates. Iyo ine akasiyana maindasitiri ekushandisa, kusanganisira kugadzirwa kweagrochemicals, resin, uye zvepakati. Inogona zvakare kushandiswa sechinhu chekutanga chekubatanidza kweakasiyana mamorekuru ane akasiyana maapplication.
Pakambani yedu, tinodada nekupa yepamusoro-mhando 2,4,5-Trifluorophenylacetic Acid kune vatengi vedu. Chigadzirwa chedu chinosangana nemhando yepamusoro-soro uye inogadzirwa ichitevera nhungamiro yakasimba kuti ive nechokwadi chekuenderana uye kuchena.
Mukupedzisa, 2,4,5-Trifluorophenylacetic Acid chinhu chinobatsira zvikuru chave chikamu chakakosha mukugadzirwa kwesitagliptin, mushonga wekutanga wechirwere cheshuga chechipiri. Kuita kwayo kwakasiyana-siyana uye kushanda kwayo kunoita kuti ive yakakosha mumaindasitiri emishonga nemakemikari, uye tinodada nekupa yepamusoro-mhando 2,4,5-Trifluorophenylacetic Acid kune vatengi vedu.
