4-[(4-Hydroxy-2-pyrimidinyl)amino]benzonitrile(CAS# 189956-45-4)

Molecular Formula	C11H8N4O
Molar Misa	212.21
Density	1.31±0.1 g/cm3(Zvakafanotaurwa)
Melting Point	>300°C
Boling Point	399.7°C pa760 mmHg
Flash Point	195.6°C
Solubility	DMSO (Zvishoma), Methanol (Zvishoma)
Vapor Presure	0-0Pa pa20-25 ℃
Chitarisiko	Solid
Color	Pale Brown kuna Brown
pKa	8.66±0.40(Zvakafanotaurwa)
Storage Condition	2-8°C
Refractive Index	1.67

Product Detail

LogP	0.9 uye pH6.6
use	4- [(4-hydroxy-2-pyrimidinyl) amino] benzonitrile inogona kushandiswa seyepakati mune organic synthesis uye yepakati yemishonga, uye inogona kushandiswa murabhoritari Organic synthesis process uye makemikari nemishonga yekutsvaga nekuvandudza maitiro.
kugadzirira	uremu 2-(methylthio) pyrimidine -4 (3H) -imwe (3g,21mmol) uye 4-aminobenzonitrile (2.99g,25mmol) mu50mL yakapoteredza pasi flask, yakachengetedzwa nenitrogen, zvishoma nezvishoma inopisa kusvika ku180 ℃, uye yakabata 8 maawa. Mushure mekunge maitiro acho atonhodzwa, 20mL yeacetonitrile inowedzerwa kuitira ultrasonic kurapwa, kusefa, keke resefa rinoshambidzwa neacetonitrile, hapana 4-aminobenzonitrile yakasara inoonekwa neTLC, uye iyo yero yero yakasimba inowanikwa nekuomesa keke yefirita ndeye 4-( (4-oxo -1, 6-dihydropyrimidine -2-yl) amino) benzonitrile ine goho re73.6%.