4-Nitrophenylacetic Acid (CAS# 104-03-0)
Application
For organic synthesis.Inonyanya kushandiswa mukurapa uye mamwe organic synthesis, uye inogona zvakare kushandiswa kutsvagisa biochemical.
Tsanangudzo
Kuonekwa yellowish-kufanana neupfu
Rura Beige kune yero
Merck 14,6621
BRN 1911801
pKa 3.85(pa25 ℃)
PH 2.98 pa22.8℃ uye 10g/L
Safety
Hazard Symbols Xi - Irritant
Irritant
Njodzi Makodhi 36/37/38 - Kushungurudza maziso, kufema system uye ganda.
Tsanangudzo Yekuchengetedza S26 - Kana wasangana nemaziso, sukurudza nekukurumidza nemvura yakawanda uye tsvaga mazano ekurapwa.
S36 - Pfeka zvipfeko zvinodzivirira zvakakodzera.
S37/39 - Pfeka magirovhosi akakodzera uye dziviriro yeziso / kumeso
UN IDs UN 3077 9 / PGIII
WGK Germany 3
RTECS AJ1130010
TSCA Hongu
HS Code 29163900
Hazard Note Irritant
Toxicity dnr-bcs 500 mg/disc MUREAV170,11,86
Kurongedza & Kuchengeta
Yakarongedzwa mumadhiramu 25kg/50kg. Storage Condition Yakavharwa mune yakaoma, Kamuri Tembiricha
Nhanganyaya
4-Nitrophenylacetic acid ikemikari yakawanda uye yakakosha inoshandiswa muorganic synthesis, kunyanya mumunda wemishonga. Inoshandiswawo mune dzakasiyana siyana biochemical research field. 4-Nitrophenylacetic acid inoshanda uye yakashandiswa zvakanyanya chivakwa chekuvaka mukugadzirwa kwemishonga yakawanda nemishonga. Hunhu hwayo hwakasiyana hunoita kuti ive reagent yakanakira kugadzirwa kwemishonga ine simba uye yakasarudzika, inobatsira kuderedza zvirwere uye kuponesa hupenyu.
4-Nitrophenylacetic Acid ihupfu hweyero-kunge hunoratidzika kunge beige kune yero muruvara. Iyo organic synthetic compound inogona kushandiswa kune dzakasiyana siyana dzekushandisa mumishonga yemishonga uye biochemical industries. Iyi kemikari inonyanya kushandiswa mune organic synthesis, iyo inoshanda sechinhu chakakosha chekuvaka chekugadzira akasiyana mamorekuru akaomarara. Hunhu hwayo hwakasiyana hunoita kuti ive chinhu chakakosha mukubatanidzwa kwemishonga yakawanda nemishonga.
4-Nitrophenylacetic acid inotorwa kubva ku phenylpropionic acid uye ine boka re nitro uye boka re carboxylic acid rakabatanidzwa kune phenyl ring. Kemikari iyi inonyungudika zvakanyanya mumvura uye nezvimwe zvinonyungudutsa polar. Yayo yakasarudzika kemikari zvimiro inoita kuti ive yakakodzera reagent yekushandisa mune yakafara dhairekitori ye organic synthesis maitiro, anosanganisira peptide synthesis, esterification, amidation, uye reductive amination.
1. Pharmaceutical Applications:
4-Nitrophenylacetic acid inoshandiswa zvakanyanya muindasitiri yemishonga, iyo inoshanda sechinhu chikuru chekuvaka mukugadzirwa kwemishonga yakasiyana-siyana. 4-Nitrophenylacetic acid inogona kushandiswa mukugadzirwa kwemishonga yekurapa kusagadzikana, asthma, cancer, cholesterol, hypertension, kuzvimba, uye kusagadzikana kwehutano hwepfungwa, pakati pevamwe.
2. Biochemical Applications:
4-Nitrophenylacetic acid inoshandiswawo zvakanyanya mukutsvagisa biochemical, iyo inoshanda senge reaction mechanism probe. Inogona kushandurwa kuita 4-nitrophenylate derivatives iyo inoshandiswa kuongorora maitiro ekufambisa erekitironi mune akasiyana enzymatic reaction maitiro. Somugumisiro weiyi probe, 4-nitrophenylacetic acid inogona kushandiswa mukuyera kwekuchinja kwekuita enzymatic kana ma substrates akasiyana akaunzwa.
Mukupedzisa, 4-Nitrophenylacetic acid ikemikari yakawanda uye yakakosha inoshandiswa muorganic synthesis, kunyanya mukugadzirwa nekugadzirwa kwemishonga. 4-Nitrophenylacetic acid inoshandiswawo munzvimbo dzakasiyana siyana dzekutsvagisa biochemical, uko inobatsira kuongorora maitiro ekufambisa erekitironi mune akasiyana enzymatic reaction maitiro. Yayo yakanaka kwazvo yemuviri uye yemakemikari zvimiro, senge yakanyanya kunyungudika mumvura, inoita kuti ive yakakosha reagent mune akasiyana organic synthesis maitiro. 4-Nitrophenylacetic acid inoshandura-shanduko mumhizha yemishonga, uko kushandiswa kwayo kwakatungamirira kukugadzirwa kwemishonga yakasiyana-siyana yakavandudza uye yakachengetedza hupenyu husingaverengeki.
