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alpha-Arbutin (CAS# 84380-01-8) Featured Image
  • alpha-Arbutin (CAS# 84380-01-8) 1

alpha-Arbutin (CAS# 84380-01-8)

Chemical Property:

Molecular Formula C12H16O7
Molar Misa 272.25
Density 1.556±0.06 g/cm3(Zvakafanotaurwa)
Melting Point 195-196°C
Boling Point 561.6±50.0 °C(Zvakafanotaurwa)
Flash Point 293.4°C
Solubility Soluble mu methanol, ethanol, DMSO uye mamwe organic solvents
Vapor Presure 1.9E-13mmHg pa25°C
Chitarisiko White crystalline powder
Color Kuchena kusvika Kuchena-Kuchena
BRN 89675
pKa 10.10±0.15(Zvakafanotaurwa)
Storage Condition 2-8°C
Refractive Index 1.65
MDL MFCD09838262
Zvenyama uye Chemical Properties Kunyungudika 195-196°C

Product Detail

Product Tags

Ngozi uye Kuchengeteka

WGK Germany 3

 

Information

Overview arbutin is a hydroquinone glycoside compound, chemical name for 4-hydroxyphenyl-d-glucopyranoside (y), iripo mubere fruit, bilberry nemimwe miti, inyowani isingatsamwisi, isingasviki, inocheneruka yezvisikwa zvinhu zvinoshanda zvine kuenderana kwakasimba. Arbutin ine mapoka maviri ekugadzirisa uye anoshanda anoshanda muhutano hwayo hwema molecular: imwe inosara yeglucose; Imwe yacho iboka re phenolic hydroxyl. Mamiriro emuviri e-α-arbutin anoita senge chena kusvika kuchena grey poda, iyo inonyanya kunyungudika mumvura uye ethanol.
kushanda zvakanaka α-arbutin ine kurapa kuri nani pamavanga anokonzerwa neUV Burns, ine zviri nani zvinopesana nekuzvimba, kugadzirisa uye kuchena mhedzisiro. Inogona kutadzisa kugadzirwa uye kuiswa kwe melanin, kubvisa mavara uye freckles.
nzira yekuita Iyo yekuchena nzira yea-arbutin inodzivirira zvakananga basa re tyrosinase, nekudaro ichidzikisa kugadzirwa kwe melanin, pane kuderedza kugadzirwa kwe melanin nekudzivisa kukura kwesero kana tyrosinase gene kutaura. Sezvo α-Arbutin iri chinhu chinoshanda uye chakachengeteka chekuchenesa chinoshanda, makambani mazhinji ezvekuzora kumba nekune dzimwe nyika atora α-arbutin pachinzvimbo che β-arbutin sekuwedzera kuchena.
Application alpha-Arbutin ikemikari yakafanana ne arbutin, inogona kutadzisa kugadzirwa uye kuiswa kwe melanin, kubvisa mavara uye freckles. Mhedzisiro yacho inoratidza kuti arbutin inogona kutadzisa kuita kwe tyrosinase panguva yakaderera, uye inhibitory mhedzisiro pa tyrosinase iri nani pane iyo arbutin. alpha-arbutin inogona kushandiswa seyakachenesa mumiriri mune zvizorwa.
kucheneswa nekuzivikanwa sampuli yakawanikwa nemhinduro yakatanga kubudiswa ne ethyl acetate, ndokuzobudiswa ne-n-butanol, masampuli akaunganidzwa nekuputika pane rotary evaporator uye centrifuged. Iyo supernatant yakaongororwa neHPLC ikaenzaniswa neHPLC chromatogram yealpha-arbutin, ingave sampuro neal-arbutin zvine nguva imwe chete yekuchengeta inoenzaniswa, uye kuti sampu ine α-Arbutin inotarirwa.

Chigadzirwa mushure mekubviswa uye kucheneswa kwakaonekwa neiyo yakanaka ion mode yeLC-ESI-MS/MS. Nekuenzanisa hukama hwemamorekuru e-α-bear muchero nehupamhi hwemamorekuru e-α-arbutin mwero, zvinogona kutariswa kana chigadzirwa chiri α-arbutin.
Usage α-arbutin inogona kurambidza tyrosinase chiitiko panguva yakaderera, iyo inhibitory mhedzisiro pa tyrosinase iri nani pane iyo arbutin.
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