ALPHA-ISO-METHYLIONONE(CAS#127-51-5)
| Hazard Symbols | Xi – Hasha |
| Risk Codes | 43 - Inogona kukonzera kunzwisiswa nekusangana kweganda |
| Tsanangudzo Yekuchengetedza | S24/25 - Dzivisa kusangana neganda nemeso. S36/37 - Pfeka zvipfeko zvekudzivirira zvakakodzera uye magurovhosi. |
| UN IDs | UN1230 - kirasi 3 - PG 2 - Methanol, mhinduro |
| WGK Germany | 2 |
| Muchetura | GRAS (FEMA). |
Nhanganyaya
introduce
Musanganiswa wemethyl uye ethyl isomethyl violet ketone uye methyl uye ethyl ortho methyl violet ketone.
nature
Alpha isomethylprednisolone ndeye organic compound. Iyo yepepuru yecrystalline yakasimba. Patembiricha yemumba, ine kunhuhwirira kwakasiyana-siyana.
Alpha isomethylprednisolone inonhuhwirira ketone. Inowanikwa kubva kumethylation reaction ye violet doro uye inonzi isomethyl violet ketone. Chimiro chayo che molecular ine ring inonhuhwirira uye ketone boka.
Pakupisa kwekamuri, yakasimba, asi inogona kunyungudutswa nekupisa. Haina kunyungudika mumvura, asi inogona kunyungudika mune mamwe organic solvents senge ethanol uye dichloromethane. Inonzwa kuchiedza uye inogona kuita photolysis reaction pasi pe ultraviolet chiedza irradiation.
Mukutaura kwemakemikari ehupfumi, α - isomethylprednisolone inhengo inoshandiswa. Inogona kusangana nekuita senge oxidation, kuderedza, kuwedzera, uye kutsiva. Inopindirana nemamwe ma electrophilic reagents kugadzira zvigadzirwa zvekuwedzera. Inogona kuve protonated pamberi peakasimba acids. Inogonawo kushandurwa kuita ketone acids kuburikidza nekuita oxidation.
Nzira yekugadzira
Iyi inotevera inzira yakajairika yekugadzira alpha isomethylprednisolone:
Kugadzirira kwezvinhu zvekutanga: Gadzirira zvinhu zvekutanga, kusanganisira Isobutyl ketone uye Cyclohexanone. Aya maumbirwo maviri akakosha precursors for synthesis ye α - isomethylprednisolone.
Maitiro ekugadzirisa mamiriro: Reacte isodecanone uye cyclohexanol pasi pemamiriro akakodzera. Mamiriro ezvinhu akajairika ndeyekuita maitiro pasi pemamiriro e acidic, uye anowanzo shandiswa acid catalysts anosanganisira sulfuric acid (H2SO4) uye phosphoric acid (H3PO4).
Matanho ekuita: Sanganisa imwe huwandu hweisodecanone uye cyclohexanol, uye wedzera acid catalyst. Zvadaro, maitiro anoitwa pane tembiricha yakakodzera, ine tembiricha inowanzoshandiswa ye50-70 degrees Celsius. Nguva yekuita kazhinji maawa akawanda kusvika makumi emaawa.
Kuparadzanisa uye kucheneswa: Mushure mekuita kwapera, chigadzirwa chinocheneswa kubva pamusanganiswa wekuita ne distillation kana dzimwe nzira dzekuparadzanisa.
Crystallization uye kuomesa: Crystallize uye woomesa chigadzirwa chakacheneswa kuti uwane yekupedzisira alpha isomethylprednisolone chigadzirwa.
