BOC-GLY-GLY-GLY-OH (CAS# 28320-73-2)

Nhanganyaya

Tert-Butoxycarbonylglycyl glycylglycine (Boc-Gly-Gly-Gly-OH) musanganiswa weorganic une zvinhu zvinotevera:

Zvakasikwa:

-Kuonekwa: kazhinji chena crystal kana crystalline powder

-Molecular formula: C17H30N4O7

-Molecular uremu: 402.44g / mol

-Kunyungudika: inenge 130-132 ° C

-Solubility: Soluble in organic solvents yakadai sedimethylformamide (DMF), dichloromethane, chloroform, nezvimwewo, isingasviki mumvura.

Shandisa:

Boc-Gly-Gly-Gly-OH inowanzoshandiswa mune organic synthesis, kunyanya semapoka ekudzivirira kana mapoka. Inogona kushandiswa seboka rinodzivirira reamino acids kudzivirira maitiro asina-chaiyo, uye inowanzoshandiswa mukugadzirisa kwechikamu chakasimba, peptide synthesis uye synthesis yezvinodhaka.

Nzira:

Nzira yakajairika yekugadzirira Boc-Gly-Gly-Gly-OH kuunza boka rekuchengetedza tert-butoxycarbonyl paboka recarboxyl reglycine. Matanho chaiwo anosanganisira:

1. Glycine inobatwa nemusanganiswa we sodium nitrite uye sulfuric acid kuwana tert-butoxycarbonyl glycinate.

2. Ester kudzivirira boka rinobviswa ne hydrolysis reaction kuti riwane Boc-glycine.

3. Dzokorora matanho ari pamusoro apa kaviri kuti uise boka recarboxyl reglycine mumapoka maviri ekudzivirira tert-butoxycarbonyl maererano kuti uwane Boc-Gly-Gly-Gly-OH.

Zvekuchengetedza

Iko kushandiswa kweBoc-Gly-Gly-Gly-OH kunofanirwa kutarisisa kune zvinotevera kuchengetedza zvinhu:

-Dzivisa kusangana neganda uye maziso, sezvo zvinogona kukanganisa ganda nemaziso.

-Pfeka magirovhosi ekudzivirira akakodzera, magirazi uye zvipfeko zvekudzivirira panguva yekushanda.

-Shandisa panzvimbo inofefetera zvakanaka kudzivirira kufema huruva kana mhute yaro.

-inofanira kuchengetwa kure nemoto, kupisa uye oxidant, chengetedza mudziyo wakavharwa, wakachengetwa munzvimbo inotonhorera, yakaoma.