Boc-L-Glutamic acid 1-benzyl ester (CAS# 30924-93-7)

Nhanganyaya

Boc-L-Glutamic acid 1-benzyl ester(Boc-L-Glutamic acid 1-benzyl ester) isanganiswa ine organic compound ine kemikari formula yeC17H19NO6 uye imwe hama molecular mass ye337.34. Iyo chena yakasimba, inonyungudika mune organic solvents senge ethanol, dimethylformamide uye chloroform.

Boc-L-Glutamic acid 1-benzyl ester inowanzoshandiswa mukugadzirwa kwepeptide compounds. Inogona kushandiswa semicellar agent kana boka rinodzivirira kuchengetedza boka reamino acid kudzivirira maitiro asina kudiwa mumativi emakemikari, uye panguva imwechete inogona kuvandudza goho. Uye zvakare, inogona zvakare kushandiswa kune synthesis ye polypeptide mishonga uye ane hukama bioactive mamorekuru.

Nzira yekugadzirira Boc-L-Glutamic acid 1-benzyl ester inowanzo kuunza boka rekudzivirira reBoc muboka reamino reglutamic acid, uye kuita esterification reaction ne benzyl anhydride ester panzvimbo iyi. Kuita kunowanzoitwa pasi pekusarerekera kana mamiriro ekutanga uye kazhinji inoda imwe nguva yenguva kuti uone kupera kwekuita. Chigadzirwa chinowanikwa chinogona kucheneswa necrystallization kana mamwe matanho ekuchenesa.

Nezve ruzivo rwekuchengetedza, iyo chaiyo chengetedzo yeBoc-L-Glutamic acid 1-benzyl ester inoda kumwe kutsvagisa uye kuongororwa. Nekudaro, semumiriri wemakemikari, inogona kunge iine kumwe kushatirwa uye chepfu. Matanho akakodzera emurabhoritari anofanirwa kuteverwa panguva yekubata kana kushandiswa, uye nzira dzekuchengetedza dzakakodzera dzinofanirwa kutorwa, kusanganisira kupfekedzwa kwemidziyo yekuzvidzivirira (semuenzaniso, magurovhosi erabhoritari, magirazi erabhoritari, nezvimwewo). Panguva yekushandiswa kana kuraswa, tsvina inofanira kuraswa zvakanaka kudzivirira kusvibiswa kwezvakatipoteredza.