BOC-L-Phenylglycine (CAS# 2900-27-8)
| Tsanangudzo Yekuchengetedza | S22 - Usafeme guruva. S24/25 - Dzivisa kusangana neganda nemeso. |
| WGK Germany | 3 |
| HS Code | 2924 29 70 |
Nhanganyaya
N-Boc-L-Phenylglycine inhengo yehupenyu inoumbwa nekuumbwa kwemakemikari bond pakati peamino group (NH2) yeglycine uye boka re carboxyl (COOH) re benzoic acid. Chimiro chayo chine boka rekudzivirira (Boc boka), iro tert-butoxycarbonyl boka, rinoshandiswa kuchengetedza reactivity yeboka reamino.
N-Boc-L-phenylglycine ine zvinotevera zvivakwa:
-Kuonekwa: White crystalline yakasimba
- Solubility: Inonyungudika mune mamwe organic solvents, senge dimethylformamide (DMF), dichloromethane, nezvimwe.
N-Boc-L-phenylglycine inowanzoshandiswa mumatanho akawanda ekuita mune organic synthesis, kunyanya yekubatanidza peptide makomisheni. Boka rinodzivirira reBoc rinogona kudzivirirwa nemamiriro ane acidic, kuitira kuti boka reamino riite reactive uye rozoita zvinozoitika. N-Boc-L-phenylglycine inogona zvakare kushandiswa seyakatorwa pakuvaka chiral nzvimbo mu peptide synthesis.
Kugadzirira kweN-Boc-L-phenylglycine kunonyanya kuitwa nematanho anotevera:
Glycine inogadzirwa ne benzoic acid kuti iwane benzoic acid-glycinate ester.
Kushandisa lithium borotrimethyl ether (LiTMP) reaction, iyo benzoic acid-glycinate ester yakasvibiswa uye yakaitwa neBoc-Cl (tert-butoxycarbonyl chloride) kuti iwane N-Boc-L-phenylglycine.
- N-Boc-L-phenylglycine inogona kutsamwisa maziso, ganda, uye nzira yekufema uye inofanira kudziviswa panguva yekushandiswa.
- Midziyo yekuzvidzivirira yega senge magurovhosi erabhoritari, magirazi ekuchengetedza, nezvimwe zvinofanirwa kupfekwa panguva yekushanda.
- Inofanirwa kuitwa munzvimbo ine mhepo inofefetera murabhoritari.
- Dzivisa kusangana neoxidants uye yakasimba asidhi paunenge uchichengeta.
- Kana ikamedzwa kana kufemerwa, tsvaga kurapwa nekukasira, uuye nemudziyo wekomboni, uye upe ruzivo rwakakodzera rwekuchengetedza kuna chiremba.
