Boc-N-beta-Trityl-L-asparagine (CAS# 132388-68-2)

Tsanangudzo Yekuchengetedza	S22 - Usafeme guruva. S24/25 - Dzivisa kusangana neganda nemeso.
WGK Germany	3
HS Code	2924 29 70
Hazard Kirasi	IRRITANT

NAA-tert-butoxycarbonyl N Γ-trityl aspartamide musanganiswa weorganic, unowanzo kutaurwa nechidimbu Boc-Phe-OtBu. Iine fomula C30H37NO4 uye ichena yakasimba.
Boc-Phe-OtBu is hydrophobic uye hainyanyi kunyungudika mumvura, asi inonyungudika zviri nyore muorganic solvents semethanol, ethanol uye dichloromethane. Yakagadzikana kune chiedza nekupisa.

Shandisa:
Boc-Phe-OtBu inonyanya kushandiswa kudzivirira mapoka uye maitiro epakati mune organic synthesis. Mune synthesis, inogona kushandiswa kuchengetedza inonhuhwirira amino acids, mukuumbwa kwepolypeptides nemapuroteni, kuchengetedza mapoka anoshanda kudzivirira kuitika kwepadivi. Mukuwedzera, inogonawo kushandiswa kugadzira mamwe maumbirwo, akadai semishonga, dhayi uye organic zvinhu.

Kugadzirira nzira:
Kugadzirira kweBoc-Phe-OtBu kunonyanya kuitwa nemakemikari reaction. Imwe nzira yakajairika ndeyekuita p-benzoic acid ine t-butyl hydroxyformate kugadzira p-tert-butoxycarbonyl benzoate. Inobva yaitwa ne triphenylamine kupa chigadzirwa chekupedzisira Boc-Phe-OtBu.

Zvekuchengetedza
Iyo Boc-Phe-OtBu yakachengeteka pasi pekushandiswa kwakajairwa. Nekudaro, sekemikari, ichiri kuda kuchengetwa uye kubatwa nemazvo. Dzivisa kusangana neakasimba oxidants, kudzivirira inhalation yeguruva uye kudzivirira kubata kweganda. Paunenge uchiishandisa, pfeka zvinodzivirira zvakakodzera, zvakadai semagirovhosi nemagirazi ekudzivirira. Muchiitiko chekusangana netsaona kana kunwa, tsvaga mazano ekurapa nekukurumidza uye kupa ruzivo kuna chiremba nezvekemikari. Mitemo yekuchengetedzwa kwenharaunda nemirairo inofanira kuteverwa pakubata nekurasa tsvina.