Chloromethyl P-Tolyl Ketone (CAS# 4209-24-9)

Chloromethyl p-tolyl ketone chinhu chakakosha chemakemikari musanganiswa unoshandiswa zvakanyanya mumaindasitiri akasiyana siyana, senge organic synthesis, chikafu nechinwiwa, uye kugadzira inonhuhwirira. Iyo inowanzozivikanwa seCMPTK uye inotorwa kubva para-tolyl ketone. Ichi chigadzirwa chichena kusvika kuchena checrystalline poda, ine kunhuhwirira kwakasiyana. Yayo yemamorekuru fomula ndeye C9H9ClO, uye inoshandiswa zvakanyanya seyakagadzirwa kugadzirwa kweakasiyana emishonga inoshanda makomisheni, agrochemicals, uye akakosha makemikari.

Iyo yakanyanya kuchena mwero yeCMPTK inoita kuti ive yakakodzera mumiriri wekubatanidza kwemakemikari mazhinji akakosha. Inonyanya kukosha mukugadzirwa kwebiologically active compounds uye sefanotangira pakugadzirwa kwemhando yepefiyumu nemishonga yekunhuhwirira. Izvo zvinhu zvakasiyana-siyana zveCMPTK zvinoita kuti ishandiswe muhuwandu hwakawanda hwekuita, kusanganisira Friedel-Crafts acylation, halogen exchange, uye base-catalyzed alkylation. Uyezve, kushandiswa kwechigadzirwa ichi kunoguma negoho repamusoro uye kuvandudzwa kwemaitiro ekuita, zvichiita kuti kugadzirwa kwezvigadzirwa zvemhando yepamusoro zvinodhura.

Muindasitiri yechikafu nechinwiwa, CMPTK inoshandiswa sechinhu chinonhuwira, kunyanya mukugadzira makuki uye zvinhu zvakabikwa. Kunhuhwirira kwayo kwakasiyana uye kunonakidza kunowedzera kunaka uye kunaka kwezvakasiyana zvigadzirwa zvekudya, nekudaro zvinovandudza ruzivo rwese rwevatengi. Pamusoro pezvo, chigadzirwa ichi chinoshandiswa kugadzira zvinonhuhwirira zvinoshandiswa mukuchengeta munhu uye zvigadzirwa zvekuchengeta pamba zvakaita seshamposi, sipo, uye zvinofefetera mhepo. Kunhuhwirira kwayo kunonakidza uye kugadzikana kwemakemikari kunoita kuti ive yakakodzera kushandiswa mune zvakasiyana zvigadzirwa, ichiwedzera kubata kweumbozha uye kuomarara kune yekupedzisira-mushandisi.

Kushandiswa kwakakosha kweCMPTK kuri mukubatanidzwa kwemishonga inoshanda makomisheni. Icho chinhu chakakosha chekutanga chekugadzira mishonga yakawanda, kusanganisira isiri-steroidal anti-inflammatory drugs (NSAIDs), mishonga yemwoyo, uye neuroprotective agents. Kushandiswa kwakawanda kweCMPTK muindasitiri yemishonga kunokonzerwa nezvinhu zvayo, zvakadai sokunyunguduka kwakanaka, high reactivity, uye kushandiswa kwakasiyana-siyana mukuita kwakasiyana-siyana. Uyezve, maitiro akavandudzwa ekuita uye mari yekuchengetedza inopihwa neCMPTK inoita kuti ive sarudzo inokwezva kumakambani anogadzira zvinodhaka.

Mukupedzisa, CMPTK inosiyana-siyana uye yakakosha kemikari komputa inowana kushandiswa kune akawanda maindasitiri. Mashandisirwo ayo akapararira mune organic synthesis, chikafu uye chinwiwa, uye kunhuhwirira kugadzira kunoita kuti ive-inofanirwa kuve nayo kune chero basa rekugadzira. Yayo yakasarudzika zvivakwa uye mutengo-kushanda kunoita kuti ive inoyevedza sarudzo kumakambani ari kutsvaga kuvandudza maitiro avo uye kuderedza mitengo yekugadzira uku vachichengetedza yakakwirira-mhando zviyero. Pakazara, CMPTK yakaratidza kuve yakavimbika komisheni seyakasvibirira yekugadzira makemikari akasiyana-siyana mumhando dzakasiyana dzemaindasitiri.