D-1-N-Boc-prolinamide (CAS# 35150-07-3)
| Hazard Symbols | Xn – Zvinokuvadza |
| Risk Codes | 22 – Zvinokuvadza kana ikamedzwa |
| Tsanangudzo Yekuchengetedza | 24/25 - Dzivisa kusangana neganda nemeso. |
| WGK Germany | 2 |
Nhanganyaya
D-1-N-Boc-prolinamide(D-1-N-Boc-prolinamide) musanganiswa une zvinhu zvinotevera:
1. Kuonekwa: White crystalline yakasimba.
2. molecular formula: C14H24N2O3.
3. Huremu hwemamorekuru: 268.35g/mol.
4. nzvimbo yakanyunguduka: inenge 75-77 degrees Celsius.
5. Solubility: Solubility mumvura uye zvimwe organic solvents, akadai chloroform, ethanol uye dimethyl sulfoxide.
Imwe yemashandisirwo makuru eD-1-N-Boc-prolinamide ndeye chiral reagent yeasymmetric synthesis muorganic chemical synthesis. Inogona kushandiswa sechivakwa che chiral skeleton kuunza ruzivo rwechiral kuburikidza neiyo chiral centre, nekudaro ichiwana chiral makomisheni. Uye zvakare, inogona zvakare kushandiswa seyepakati pakubatanidzwa kwemishonga, mishonga yezvipembenene uye bioactive mamorekuru.
Nzira yekugadzirira D-1-N-Boc-prolinamide inowanzoita kuti N-Boc-L-proline ine tert-butyl chloroformate pasi pemamiriro ealkaline kuti ibudise yepakati N-Boc-L-proline methyl ester, uyezve kupisa kurapwa gadzira icho chinonangwa chigadzirwa.
Nezve ruzivo rwekuchengetedza, yakadzama toxicological zvidzidzo zviri D-1-N-Boc-prolinamide kushaya. Nekudaro, kazhinji, maitiro ekuchengetedza marabhoritari echinyakare anofanirwa kuteverwa, uye matanho ekudzivirira akadai semagirovhosi, magirazi uye zvipfeko zvekudzivirira zvinofanirwa kutariswa kana uchishandisa. Mukuwedzera, inofanira kuchengetwa mumudziyo wakavharwa kuti usasangana neokisijeni uye unyoro. Kana ukafemerwa netsaona kana kuti wasangana neganda nemaziso, sukurudza nekukurumidza nemvura yakawanda uye tsvaga rubatsiro kuna chiremba. Kana tsvina ichizoraswa, mitemo yemunharaunda inofanira kuteverwa. Zvakanakisa kushandisa uye kubata komboni pasi pekutungamirwa nemumwe munhu ane hunyanzvi hwekuita chemistry.
