Fmoc-L-2-Aminobutyric acid (CAS# 135112-27-5)

Tsanangudzo Yekuchengetedza	S22 - Usafeme guruva. S24/25 - Dzivisa kusangana neganda nemeso.
WGK Germany	3
HS Code	2924 29 70
Hazard Kirasi	IRRITANT

L-2-(fluorenylmethoxycarbonylamino) butyric acid, inozivikanwawo seFmoc-glutamic acid (L-2-(9-fluorenylmethoxycarbonylamino) butyric acid), inhengo yehupenyu. Inotevera rondedzero yezvimwe zvezvivakwa zvayo, kushandiswa, nzira uye ruzivo rwekuchengetedza:

Zvakasikwa:
-Kuonekwa: isina ruvara kana zvishoma yellow crystalline poda;
-Molecular formula: C26H23NO4;
-Molecular uremu: 413.47g / mol;
-kunyungudika: inenge 166-168 ℃;
-Solubility: Fmoc-glutamic acid inonyungudika mune organic solvents yakadai sedimethylformamide uye hydrofluoric acid.

Shandisa:
Fmoc-glutamic acid, sechikwata chekudzivirira cheboka, chinowanzoshandiswa mu peptide synthesis, kunyanya mukugadzirwa kwepeptide yakagadzikana sequences uye synthesis yeLevenstein peptides (Levenshtein peptide). Inogona kushandiswa seyakagadzirwa yepakati yeamino acids, kana kushandiswa mune yakasimba chikamu synthesis, yakakwira performance liquid chromatography, nezvimwe.

Kugadzirira nzira:
Kugadzirira kweFmoc-glutamic acid kazhinji kunosanganisira matanho anotevera:
1. Mune anhydrous system, L-glutamic acid inoshandiswa neFmoc-OSu (fluorenylmethoxycarbonyl-chloro anhydride), uye sodium chloride (NaCl) inoshandiswa kukurudzira maitiro ekugadzira Fmoc-glutamic acid Fmoc-A munyu.
2. Nokuda kweFmoc-glutamic acid munyu, inonyungudutswa mune yakanyungudutswa (yakadai se dimethylformamide) uye inoiswa kune nzira yakakodzera yekuchenesa (yakadai secrystallization) kuwana Fmoc-glutamic acid.

Zvekuchengetedza
Fmoc-glutamic acid inowanzogadzikana uye yakaderera muchetura pasi pekushanda kwemaitiro. Asi semusanganiswa weorganic, uchiri kufanira kutarisisa kune anotevera ekuchengetedza matanho:
-Dzivisa inhaling guruva, kusangana neganda uye maziso;
-Panguva yekushanda, pfeka magurovhosi ekudzivirira, magirazi uye zvipfeko zvekudzivirira zvinosangana nekuchengetedza zvinodiwa;
-Shanda munzvimbo ine mhepo inofefetera zvakanaka kudzivirira kuratidzwa kwakananga kwenguva yakareba;
-Kana tsvina kubva mukomboni iyi ichizoraswa, inofanira kuraswa zvakanaka maererano nemitemo yenzvimbo.