fmoc-L-4-hydroxyproline (CAS# 88050-17-3)

Nhanganyaya

Fmoc-L-hydroxyproline (Fmoc-Hyp-OH) inotorwa neamino acid ine zvinotevera zvivakwa uye mashandisiro:

Hunhu:

-Kuonekwa: Ichena kana isina-chena crystalline poda

- Solubility: Soluble mune organic solvents seDMF, DMSO uye methanol

- pKa kukosha: 2.76

Shandisa:

- Fmoc-Hyp-OH inonyanya kushandiswa peptide synthesis uye peptide synthesis mune yakasimba-chikamu synthesis.

-Inoita sechikamu cheboka rinodzivirira kuchengetedza mativi echeni anoshanda mapoka eamino acids panguva yakasimba-chikamu synthesis kudzivirira kuita kusingatarisirwi uye kuchengetedza kusarudza.

Nzira:

Fmoc-Hyp-OH inogona kugadzirirwa nekuita Fmoc-amino acids neL-hydroxyproline mune yakakodzera solvent. Mamiriro ekuita anowanzo sanganisira tembiricha yakakodzera yekuita uye yakakodzera base catalyst, senge N,N-dimethylpyrrolidone (DMAP). Chigadzirwa chinoguma chinocheneswa nematanho akadai sekunaya kwemvura, kuwacha, nekuomesa.

Zvekuchengetedza

- FMOC-HYP-OH ndeye organic musanganiswa uye inofanirwa kubatwa zvinoenderana nerabhoritari chengetedzo protocol.

- Iyo guruva inogona kuvharidzirwa uye inosangana neganda, saka kuchenjerera kunofanira kutorwa kuti usapinda zvakananga kana kubata.

- Panguva yekuitwa, midziyo yekudzivirira yakakodzera senge magirovhosi erabhoritari, dziviriro yeziso, zvipfeko zvekudzivirira, nezvimwe zvinofanirwa kupfekwa.

- Inofanira kuchengetwa yakavharwa zvakasimba munzvimbo yakaoma, inotonhorera, kure nemoto uye zvinhu zvinopisa.