Fmoc-L-Aspartic acid-1-benzyl ester (CAS# 86060-83-5)

Nhanganyaya

Fmoc-Asp-OBzl(Fmoc-Asp-OBzl) ikamu rinonyanya kushandiswa mukugadzirwa kwepeptide uye kuumbwa kwakasimba kwechikamu.

Zvakasikwa:

Fmoc-Asp-OBzl ichena crystalline yakasimba ine yakanaka solubility uye kugadzikana. Mushonga wayo wemakemikari ndeye C33H29NO7 uye uremu hwayo hwemamorekuru ndeye 555.6. Iine fluorenyl kudzivirira boka (Fmoc) uye benzoyl kudzivirira boka (Bzl) kudzivirira aspartic acid.

Shandisa:

Fmoc-Asp-OBzl seboka rinodzivirira rinogona kushandiswa mukugadzirwa kwepeptides nemapuroteni. Inogona kuiswa kune yakasimba chikamu synthesis tekinoroji uye inodzivirira yekubvisa boka nhanho mune peptide synthesis reaction. Mukubatanidza, iyo aspartic acid inosara inogona Fmoc-Asp-OBzl kuchengetedzwa mune inoguma peptide chidimbu kudzivirira kuita kusingadiwe.

Kugadzirira nzira:

Kugadzirira kweFmoc-Asp-OBzl kunowanzoitwa nemakemikari synthesis. Kunyanya, Fmoc-Asp-OBzl inogona kuwanikwa nekuita fluorenecyl chloride (Fmoc-Cl) ine aspartic acid -1-benzyl ester (Asp-OBzl).

Zvekuchengetedza

Fmoc-Asp-OBzl ikemikari inoda kubatwa murabhoritari. Tevedzera maitiro akakodzera ekuchengetedza murabhoritari panguva yekubata, sekupfeka midziyo yekudzivirira yakakodzera (senge magirovhosi, magirazi, uye majasi emurabhoritari) kudzivirira kubata ganda, maziso, uye nzira yekufema. Mukuwedzera, inofanira kuchengetwa munzvimbo yakaoma, inotonhorera, uye kure nemoto uye zvinhu zvinopisa. Paunenge uchishandisa Fmoc-Asp-OBzl, kutarisisa kunofanirwa kubhadharwa kune huturu hwayo uye kushatirwa, uye kuve nechokwadi kuti inoshandiswa munzvimbo yakachengeteka.