Fmoc-L-glutamic acid-gamma-benzyl ester (CAS# 123639-61-2)

Fluorene methoxycarbonyl-L-glutamic acid-Γ-benzyl musanganiswa unoshandiswa mu peptide synthesis mune solid-phase synthesis. Hunhu hwayo:
- Chitarisiko: Chichena kusvika kucheneruka chakasimba
- Solubility: Fmoc-L-Glu(OtBu)-OH ine yakanaka solubility pakati pezvakajairwa organic solvents.

Iko kushandiswa kukuru kweFmoc-L-Glu (OtBu)-OH iboka rinodzivirira mu peptide synthesis. Paunenge uchigadzira peptide cheni, Fmoc-L-Glu(OtBu)-OH inosunga kumaamino acids, ichidzivirira basa ravo kubva kune zvisiri-chaiyo maitiro nezvimwe zvinogadzirisa. Mushure mokunge mhinduro yacho yapera, Fmoc-L-Glu (OtBu) -OH inogona kubviswa nekubvisa boka rinodzivirira kudzorera basa reamino acids.

Kugadzirira kweFmoc-L-Glu(OtBu)-OH kwakaoma uye kazhinji kunoda kushandiswa kwenhevedzano yematanho ekugadzira organic. Glutamic acid inobatwa nebromoacetate kuwana ethyl glutamate. Zvadaro, ethyl glutamate inobatwa ne benzyl doro kugadzira ethyl glutamate benzyl doro ester. Ethyl glutamate benzyl alcohol ester yakaitwa neFmoc-Cl kugadzira iyo yakanangwa chigadzirwa Fmoc-L-Glu(OtBu)-OH.

Ruzivo Rwekuchengetedza: Fmoc-L-Glu(OtBu)-OH mushonga wemurabhoritari uye unoda kushandiswa pasi pekushanda kwakachengeteka murabhoritari. Tevedzera maitiro ekuchengetedza murabhoritari zvakajairwa, kusanganisira kupfeka midziyo yekuzvidzivirira (semu, magirovhosi emurabhoritari, magirovhosi, nezvimwewo), kudzivirira kubata kweganda nekufemesa, uye kushanda murabhoritari inofefeterwa zvakanaka. Mushonga wacho unofanirwa kuchengetwa mumudziyo usina mhepo, kure nekupisa uye oxidants.