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Fmoc-O-tert-butyl-L-tyrosine (CAS# 71989-38-3) Mufananidzo
  • Fmoc-O-tert-butyl-L-tyrosine (CAS# 71989-38-3) 1

Fmoc-O-tert-butyl-L-tyrosine (CAS# 71989-38-3)

Chemical Property:

Molecular Formula C28H29NO5
Molar Misa 459.53
Density 1.218±0.06 g/cm3(Zvakafanotaurwa)
Melting Point ~150°C (Zvita.)
Boling Point 658.2±55.0 °C(Zvakafanotaurwa)
Kutenderera kwakananga(α) -28 º (c=1, DMF)
Flash Point 351.9°C
Solubility Chloroform (Zvishoma), DMF (Zvishoma), Methanol (Zvishoma)
Vapor Presure 3.2E-18mmHg pa25°C
Chitarisiko White crystal
Color Chena
BRN 4216652
pKa 2.97±0.10(Zvakafanotaurwa)
Storage Condition Chengetedza pasi pe +30°C.
Refractive Index -30 ° (C=1, DMF)
MDL MFCD00037129
Zvenyama uye Chemical Properties White crystalline powder; Isinganyunguriki mumvura uye petroleum ether, soluble mu ethyl acetate, methanol uye DMF;mp iri 150-151 ℃; Kutenderera chaiko kwemaziso [α]20D 10 5.2 °(0.5-2.0 mg/ml, ethyl acetate),[α]20D-27.6 °(0.5-2.0 mg/ml,DMF),[α]20D-6 °(0.5- 2.0 mg/ml, methanol).

Product Detail

Product Tags

Hazard Symbols Xi – Hasha
Risk Codes 36/37/38 - Kushungurudza maziso, kufema system uye ganda.
Tsanangudzo Yekuchengetedza S26 – Kana wasangana nemaziso, sukurudza nekukurumidza nemvura yakawanda uye tsvaga mazano ekurapwa.
S24/25 - Dzivisa kusangana neganda nemeso.
WGK Germany 3
HS Code 2924 29 70

 

Nhanganyaya

Fluorene methoxycarbonyl-oxotert-butyl-tyrosine ikemikari yemakemikari inowanzopfupikiswa se FMOC-Tyr(tBu)-OH. Iyi inotevera sumo kune hunhu hwayo, kushandiswa, kugadzirira uye ruzivo rwekuchengetedza:

 

Hunhu:

- Kutaridzika: Ichena kana isina-chena yakasimba.

- Solubility: Inonyungudika mune mamwe organic solvents, senge dimethyl sulfoxide uye dimethylformamide.

 

Shandisa:

- Kudzivirira mapoka mumakemikari synthesis: Mapoka eFOC anogona kushandiswa kuchengetedza mapoka emamino mumakemikari e phenolic kudzivirira kuti asaite. FMOC-Tyr(tBu) -OH inogona kushandiswa sechinhu chekutanga kugadzirira peptide cheni mumakemikari synthesis.

 

Nzira:

Iyo nzira yekugadzirira yeFOC-Tyr(tBu)-OH inogona kuwanikwa nematanho anotevera:

- Fluorenyl chloride (FMOC-Cl) inobatwa ne tert-butyl (tBu-NH2) kupa fluorenylmethoxycarbonyl-tert-butichsyl (FMOC-tBu-NH-).

- Wobva waita iyo yakaguma FMOC-tBu-NH- ine tyrosine (Tyr-OH) kugadzira FMOC-Tyr(tBu)-OH.

 

Zvekuchengetedza

-Kushandiswa kweFOC-Tyr (tBu)-OH kunoenderana nekutevedzwa kwemaprotocol ekuchengetedza marabhoritari.

- Dzivisa kusangana neganda nemeso, uye pfeka magirovhosi ekudzivirira uye magirazi paunenge uchishandisa.

- Shandisa munzvimbo ine mhepo inofefetera, kure nemoto uye zvinopisa.

- Haifanirwe kuburitswa munzvimbo uye inofanirwa kubatwa uye kuraswa zvinoenderana nemirairo yenzvimbo.

 

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