L-Pyroglutamic acid CAS 98-79-3
Ngozi uye Kuchengeteka
| Hazard Symbols | Xi – Hasha |
| Risk Codes | 36/37/38 - Kushungurudza maziso, kufema system uye ganda. |
| Tsanangudzo Yekuchengetedza | S26 – Kana wasangana nemaziso, sukurudza nekukurumidza nemvura yakawanda uye tsvaga mazano ekurapwa. S36 - Pfeka zvipfeko zvinodzivirira zvakakodzera. S37/39 - Pfeka magirovhosi akakodzera uye dziviriro yeziso / kumeso |
| WGK Germany | 3 |
| RTECS | TW3710000 |
| FLUKA BRAND F CODES | 21 |
| TSCA | Ehe |
| HS Code | 29337900 |
| Hazard Kirasi | IRRITANT |
Reference
| Reference Ratidza zvimwe | 1. [KANA=1.902] Zhi Rao et al.”Multicomponent kutsunga kwekugadzirwa kwemishonga yechivanhu yekuChina yin-zhi-huang inje… |
Basic information
oxidized proline inozivikanwawo seL-pyroglutamic acid. Relative molecular mass 129.12. Nzvimbo yakanyungudika yaive 162-163 °c. Usanyungudika mu ether, ethyl acetate-soluble, soluble mumvura (25 ° C 40), ethanol, acetone uye acetic acid. Chaicho optical rotation -11.9 °(c = 2,H2O). Munyu waro wesodium unogona kushandiswa sechinhu chinonyorovesa muzvizoro, maitiro ayo anonyorovesa ari nani pane glycerol, sorbitol, isiri-chepfu, isina simba rinokurudzira, rekuchengetedza ganda uye bvudzi rekuchengetedza zvizoro; Ichi chigadzirwa chine inhibitory mhedzisiro pane tyrosine oxidase, inogona kudzivirira kuiswa kwemelanin-senge, ine chena mhedzisiro paganda; Iine kupfava paganda, inogona kushandiswa kwezvipikiri zvizorwa; Inogona zvakare kushandiswa seyakagadzika kune yekugezesa; Makemikari reagents, ekugadzirisa kwemaminera emakwikwi; Organic intermediates.
| Nhanganyaya | pyroglutamic acid ine 5-oxyproline. Inoumbwa nekuderera kwemvura pakati pe-α-NH2 boka uye γ-hydroxyl boka re glutamic acid kuti riite molecular lactam bond; Inogonawo kuumbwa nekurasikirwa neboka reAmido mune glutamine molecule. Kana kushomeka kweglutathione synthetase kunogona kukonzera pyroglutamemia, nhevedzano yezviratidzo zvekiriniki. Pyroglutamemia chirwere che organic acid metabolism chinokonzerwa nekushomeka kweglutathione synthetase. Clinical zviratidzo zvekuzvarwa 12 ~ 24 maawa ekutanga, kufambira mberi kwehemolysis, jaundice, kusingaperi Metabolic Acidosis, kusagadzikana kwepfungwa, nezvimwewo; Weti ine pyroglutamic acid, lactic acid, Alpha deoxy4 glycoloacetic acid lipid. Kurapa, symptomatic, teerera kugadzirisa kudya mushure mezera. |
| properties | L-pyroglutamic acid, inozivikanwawo seL-pyroglutamic acid, L-pyroglutamic acid. Kubva pamusanganiswa we ethanol ne petroleum ether mukunaya kwe Crystal isina ruvara orthorhombic kaviri koni, inonyungudika ye162~163 ℃. Soluble mumvura, doro, acetone uye acetic asidhi, ethyl acetate-soluble, insoluble mu ether. Chaicho optical rotation -11.9 °(c = 2,H2O). |
