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Metadoxine (CAS# 74536-44-0) Featured Image
  • Metadoxine (CAS# 74536-44-0) 1

Metadoxine (CAS# 74536-44-0)

Chemical Property:

Molecular Formula C8H11NO3.C5H7NO3
Molar Misa 298.293
Melting Point 102-104°C
Solubility DMSO (Zvishoma), Methanol (Zvishoma)
Chitarisiko Solid
Color Ichena kusvika kuChiedza Yero
Storage Condition Yakavharwa pakaoma, 2-8°C
Shandisa Kutemerwa zvemukati neHPLC
In vitro kudzidza Panguva imwe chete Metadoxine kurapwa kunonyanya kurambidza adipogenic kusiyanisa nenzira inotsamira mudosi. Metadoxine kurapwa kubva pazuva 4 kusvika pazuva 8 inodiwa kune inhibition yeMDI-induced preadipocyte musiyano. Metadoxine inodzivirira kupera kwe glutathione uye kuwedzera kwe lipid peroxidation kukuvara kunokonzerwa ne ethanol uye acetaldehyde muHepG2 masero. Mune hepatic stellate masero, Metadoxine inodzivirira kuwedzera kwe collagen uye attenuated TNF-α secretion inokonzerwa neacetaldehyde. Nekudaro, Metadoxine inogona kubatsira mukudzivirira kukuvadzwa kunogadzirwa mukutanga kwechirwere chechiropa chedoro sezvo ichidzivirira kusaenzana kweredox yehepatocytes uye kudzivirira TNF-α induction, chimwe chezviitiko zvekutanga mukukuvara kwechiropa.

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Nhanganyaya

Metadoxin, kemikari inozivikanwa seN,N-dimethylformamide, imvura isina ruvara. Zvimiro zvayo ndezvizvi:

 

Zvimiro zvemuviri: Metadoxine imvura isina ruvara ine kunhuhwirira kwakashata, inoshanduka patembiricha yekamuri, inosanganiswa nemvura uye inowanzozivikanwa organic solvents.

 

Kemikari zvivakwa: Metadoxine ikamu rinodzikisira zvakanyanya rinogona kudhindwa nesodium hydroxide kana sodium carbonate mhinduro kugadzira formamide uye methanol.

 

Kushandisa metaxacin:

 

Catalyst: Metadoxine inogona kushandiswa semutakuri wesimbi zvinokonzeresa, uye inoshandiswa kukonzeresa maitiro ekuita kwemaamine mune organic synthesis.

 

Solvents: Metadoxine inoshandiswa zvakanyanya sechinhu chinonyungudutsa mune organic synthesis, senge kunyungudutsa simbi complexes, mapolymers, uye epakati kuitira catalytic reactions.

 

Nzira yekugadzirira: Kugadzirira kwemetadoxine kunowanzo kuwanikwa nekuita kwe formamidine uye formic acid.

 

Ruzivo rwekuchengetedza: Metaxacin inotsamwisa uye inoparadza, uye ine mhedzisiro inoshatirisa paganda, maziso uye mucous membranes. Kuchengetedza kunofanira kutorwa kudzivirira kusangana kwakananga neganda nemeso, uye magirovhosi ekudzivirira uye magirazi anofanira kupfekwa kana zvichidikanwa. Kuchenjerera kunofanira kubhadharwa kune ventilation panguva yekushandiswa kudzivirira kufema mhute dzayo. Meltadoxine chinhu chinopisa uye chinofanirwa kuchengetedzwa kure nemirazvo yakavhurika uye tembiricha yakanyanya.

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