N-Cbz-D-Tryptophan(CAS# 2279-15-4)

Nhanganyaya

N(^ a)-Benzyloxycarbonyl-D-tryptophan(N(^ a)-Benzyloxycarbonyl-D-tryptophan) ikemikari, inozivikanwawo seCBZ-D-Trp. Inotevera rondedzero yehunhu hwayo, kushandiswa, kugadzira uye ruzivo rwekuchengetedza:

Zvakasikwa:

N(^ a) -Benzyloxycarbonyl-D-tryptophan ichena kusvika kuyero yekristaro yakasimba. Iyo yakanyatsogadzikana pakupisa kwekamuri uye inogona kuchengetwa kwenguva yakareba pasi pemamiriro eanhydrous. Hainyungudike mumvura, asi inonyungudika mune zvimwe organic solvents senge methanol uye dimethyl sulfoxide.

Shandisa:

N (^ a) -Benzyloxycarbonyl-D-tryptophan inowanzoshandiswa semapoka ekudzivirira mukugadzirwa kwehupenyu, kunyanya mumakemikari peptide synthesis. Kushandiswa kwayo kukuru kwakafanana nekutorwa kwemaamino acids ekugadzirwa kwemamodule chaiwo mu polypeptide kana mapuroteni cheni. Inogona kuita basa rinokosha mukugadzirwa kwemishonga mitsva nenzira iyi.

Nzira:

Kugadzirira kweN (^ a) -Benzyloxycarbonyl-D-tryptophan inowanzoitwa nemakemikari synthesis. Chekutanga, benzyl doro uye kabhoni dhaikisaidhi inobatwa kuita benzyloxycarboxylic acid, uyezve amino acid tryptophan uye benzyloxycarboxylic acid inosimbiswa kuti iwane chigadzirwa cheCBZ-D-Trp. Kuita kunoda rubatsiro rwezvimwe organic catalysts uye solvents.

Zvekuchengetedza

N(^ a) -Benzyloxycarbonyl-D-tryptophan ine ruzivo rushoma rwekuchengetedza, asi zvichienderana neruzivo rwuripo, inowanzoonekwa seine chepfu. Kuratidzwa kwenguva refu kana kuratidzwa zvakanyanya kunogona kuve nemhedzisiro yehutano husina kunaka. Naizvozvo, matanho akakodzera ekuchengetedza anofanirwa kutorwa kana uchishandisa, kuchengetedza uye kubata iyi komputa, kusanganisira kupfeka yakakodzera midziyo yekudzivirira uye kubata munzvimbo ine mhepo inofefetera. Panguva imwecheteyo, zvinodikanwa kutevedzera maitiro ekuchengetedza akakodzera uye nzira dzekurasa.

Ndokumbira utarise kuti chinyorwa ichi chingori mhedziso yekomboni iri mubvunzo, uye iyo chaiyo yekushandisa uye kuongororwa kwenjodzi kunofanirwa kuitwa mune yakatarwa nzvimbo yerabhoritari. Usati washandisa chero chinhu chemakemikari, ndapota ita shuwa yekudzidza ruzivo rwakakodzera zvakadzama uye bvunza nyanzvi pamberi.