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N-Cbz-L-Threonine (CAS# 19728-63-3) Mufananidzo
  • N-Cbz-L-Threonine(CAS# 19728-63-3) 1

N-Cbz-L-Threonine(CAS# 19728-63-3)

Chemical Property:

Molecular Formula C12H15NO5
Molar Misa 253.25
Density 1.2499 (yakashata fungidziro)
Melting Point 101-103°C(lit.)
Boling Point 396.45°C (yakaomarara fungidziro)
Kutenderera kwakananga(α) -4.7 º (c=4, acetic acid)
Flash Point 261.3°C
Solubility inenge yakajeka muMethanol
Vapor Presure 3.7E-11mmHg pa25°C
Chitarisiko Upfu hwekristaro hwakachena kusvika kuchiedza
Color Kuchena kusvika Kunenge kuchena
BRN 2335409
pKa 3.58±0.10(Zvakafanotaurwa)
Storage Condition Yakavharwa pakaoma,Chengeta mufiriji, pasi pe -20°C
Refractive Index -4.9 ° (C=2, AcOH)
MDL MFCD00065948
Shandisa Inoshandiswa kune biochemical reagents, peptide synthesis.

Product Detail

Product Tags

Ngozi uye Kuchengeteka

Hazard Symbols Xn – Zvinokuvadza
Risk Codes R20/21/22 – Zvinokuvadza nekufema, kubata ganda uye kana ikamedzwa.
R36/37/38 - Kushungurudza maziso, kufema system uye ganda.
Tsanangudzo Yekuchengetedza S22 - Usafeme guruva.
S24/25 - Dzivisa kusangana neganda nemeso.
S36 - Pfeka zvipfeko zvinodzivirira zvakakodzera.
S26 – Kana wasangana nemaziso, sukurudza nekukurumidza nemvura yakawanda uye tsvaga mazano ekurapwa.
WGK Germany 3
HS Code 29242990

 

 

N-Cbz-L-Threonine (CAS# 19728-63-3) Information

kugadzirira wedzera 50mL yeL-Thr(30mmol) uye yakatonhodzwa yakazara Na2CO3 mhinduro mu250mL reaction bhodhoro, uye kurunga nekunyungudika muchando chekugeza. Donhedza 20mL yeZ-OSu(39.4mmol) acetone solution mubhodhoro rekuita; Kurudzira maitiro pa25 ℃, TLC-UV fluorescence uye ninhydrin ruvara nzira yekutarisa maitiro ekuita. Mushure mekuita, wedzera H2O20mL, bvisa neEt2O (30mL × 2) pa pH> 9, unganidza chikamu chemvura, gadzirisa pH kusvika 3 ~ 4 ne 1.5NHCl, bvisa neEtOAc (30mL × 3), batanidza chikamu chehupenyu, geza neakazara NaCl solution (25mL × 2), yakaoma neanhydrous Na2SO4, tarisa kuchena ne TLC-ultraviolet fluorescence uye ninhydrin color yekuvandudza nzira, uye inoputika pasi pekumanikidzwa kwakaderedzwa, vacuum kuomesa kuti uwane yero ine mafuta mvura N-benzyloxycarbonyl-L-threonine, iyo inochengetwa pakadzika tembiricha.
Shandisa CBZ-L-threonine ndiyo N-Cbz yakachengetedzwa fomu yeL-threonine (T405500). L-threonine yakakosha amino acid uye inowanzoshandiswa sechikafu uye chekuwedzera chikafu. Iyo mutant strain yeEscherichia coli yakagadzira yakawanda yeL-threonine yekutsvaga uye nekudya chikafu chinangwa. L-threonine inongowanikwa muhove nemuhuku uye inosanganisirwa mune mamwe mapuroteni akakosha emuviri, senge hemoglobin uye insulin.
Inoshandiswa kune biochemical reagents uye peptide synthesis.

 

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