NN-Bis 9-fluorenylmethyloxycarbonyl-L-histidine CAS 98929-98-7

Tsanangudzo Yekuchengetedza	S22 - Usafeme guruva. S24/25 - Dzivisa kusangana neganda nemeso.
HS Code	29242990

N(alpha),N(im)-di-fmoc-L-histidine(N(alpha),N(im)-di-fmoc-L-histidine) mushonga unowanikwa nechemical reaction ye9-fluorenecinol uye L. -histidine. Mushonga wayo wemakemikari ndeye C42H38N4O8 uye huwandu hwayo hwema molecular mass ndeye 722.78g/mol.N(alpha),N(im)-di-fmoc-L-histidine ikomboni inodzivirira amino acids uye inoshandiswa zvakanyanya muorganic synthesis uye biochemical reactions. . Inonyanya kushandiswa kudzora chimiro cheprotein uye basa, pamwe nekuwedzera nekuvandudza huwandu hwemashandisirwo emaketani epolypeptide. Mushonga uyu unoshandiswa zvakanyanya mune yakasimba chikamu synthesis matekiniki ekugadzirisa iyo N-terminus uye histidine masara epeptide uye mapuroteni mamorekuru.

Nzira yekugadzirira N(alpha),N(im)-di-fmoc-L-histidine inowanzobatanidza matanho matatu. Kutanga, ethylene glycol dimethyl ether uye diazotoluene yakaitwa pasi pecatalysis ye cuprous chloride kugadzira 9-fluorenmethanol. Zvadaro, 9-fluorenecinol uye L-histidine inoshandiswa pasi pemamiriro e acidic kuti iwane N (alpha), N (im) -di-fmoc-L-histidine. Pakupedzisira, chigadzirwa chakachena chinowanikwa nekristalllization uye matanho ekuchenesa.

Nezve ruzivo rwekuchengetedza, N(alpha),N(im)-Hakuna akawanda akakodzera tsvakiridzo mishumo pamusoro pekuchengetedzwa chaiko kwedi-fmoc-L-histidine, saka kungwarira kunodiwa. Kana ichishandiswa murabhoritari, matanho akakodzera ekuchengetedza anofanirwa kutorwa, kusanganisira kupfeka midziyo yekudzivirira yakakodzera, senge magirovhosi nemagirazi emurabhoritari, uye kudzivirira kubata ganda nemaziso. Panguva imwecheteyo, inofanira kuchengetwa mumudziyo wakaoma, wemhepo uye wakavharwa, kure nemoto uye zvinhu zvinopisa. Kuti uwane ruzivo rwakadzama rwekuchengetedza, zvinokurudzirwa kubvunza mabhuku akakodzera kana kubvunza nyanzvi.