Sodium nitroprusside dihydrate (CAS# 13755-38-9)

Chemical Property:

Molecular Formula	C5H4FeN6Na2O3
Molar Misa	297.95
Density	1.72
Mvura Solubility	Soluble mumvura. Zvishoma soluble ethanol.
Solubility	Soluble mumvura (400 g/l) pa20 °C, uye ethanol (inonyungudika zvishoma).
Chitarisiko	Kirasi tsvuku yakadzika
Specific Gravity	1.72
Color	Ruby mutsvuku
Exposure Limit	ACGIH: TWA 1 mg/m3NIOSH: IDLH 25 mg/m3; TWA 1 mg/m3
Merck	14,8649
PH	5 (50g/l, H2O, 20℃)
Storage Condition	2-8°C
Sensitive	Hygroscopic
MDL	MFCD00149192
Zvenyama uye Chemical Properties	Red-brown crystalline powder, isina kunhuwa; Kusanaka.
Shandisa	Inoshandiswa seyakagadziriswa kugadzirisa aldehydes, acetone, sulfur dioxide, zinc, alkali simbi, sulfides, nezvimwe.
In vitro kudzidza	Sodium Nitroprusside inoshanda vasodilator. Sodium nitroprusside ine inoshanda vasodilatory mhedzisiro mu arterioles uye venules. Sodium Nitroprusside inoputsika mukutenderera kuburitsa nitric oxide (NO). HAPANA inomisa guanylate cyclase muvascular smooth muscle uye inowedzera intracellular cGMP kugadzirwa. Izvi pakupedzisira zvinotungamirira mukuzorodza kwevascular smooth muscle, iyo inoderedza tsinga dzeropa. Sodium nitroprusside inoderedza kuwanda kwevascular smooth muscle.
In vivo kudzidza	Sodium nitroprusside (5 mg / kg) se nitric oxide donor zvakanyanya kuderedza intestinal ischemia-reperfusion kukuvara mumakonzo.

Tumira email kwatiri

Product Detail

Product Tags

Ngozi uye Kuchengeteka

Risk Codes	R25 – Muchetura kana ukamedzwa R26/27/28 – Muchetura wakanyanya kana ukafema, kana ukabatwa neganda uye ukamedzwa.
Tsanangudzo Yekuchengetedza	S45 - Kana waita tsaona kana ukanzwa usinganzwe zvakanaka, tsvaga rubatsiro rwekuchipatara nekukasika (ratidza chinyorwa pese pazvinogoneka.) S36/37/39 - Pfeka zvipfeko zvekudzivirira zvakakodzera, magurovhosi uye kudzivirira kweziso/chiso. S22 - Usafeme guruva.
UN IDs	UN 3288 6.1/PG 3
WGK Germany	3
RTECS	LJ8925000
FLUKA BRAND F CODES	3
TSCA	Ehe
HS Code	28372000
Hazard Kirasi	6.1
Packing Group	III
Muchetura	LD50 nemuromo muTsuro: 99 mg/kg

13755-38-9 - Reference

Reference

Ratidza zvimwe

1. Tian, Ya-qin, nevamwe. "Kuenzaniswa kwemaitiro akasiyana ekubvisa uye optimization yeiyo microwave-inobatsirwa extrac ...

13755-38-9 - Nhanganyaya

Soluble mumvura, zvishoma soluble mudoro. Mushonga wayo une aqueous hauna kugadzikana uye unogona kupera zvishoma nezvishoma uye kusvibira.

13755-38-9 - Reference Information

sumo	sodium nitroprusside (molecular formula: Na2[Fe(CN)5NO]· 2H2O, zita remakemikari: sodium nitroferricyanide dihydrate) inokurumidza kuita uye ipfupi-acting vasodilator, iyo inoshandiswa nekiriniki yekukurumidza hypertension senge hypertension, hypertensive encephalopathy, yakaipa hypertension, paroxysmal hypertension pamberi uye mushure mekuvhiyiwa pheochromocytoma, nezvimwewo, inogona kushandiswawo controlled hypotension panguva yekuvhiya anesthesia.
effect	sodium nitroprusside ine simba inokurumidza-inobata vasodilator, ine yakananga dilation mhedzisiro pane arterial uye venous yakatsetseka tsandanyama, uye inoderedza peripheral vascular resistance nekudzikisa tsinga dzeropa., Gadzira antihypertensive effect. Vascular dilation inogonawo kuderedza mutoro musati uye shure kwemoyo, kunatsiridza kubuda kwemwoyo, uye kuderedza ropa reflux kana valve isati yavharwa, kuitira kuti zviratidzo zvekukundikana kwemoyo zvisunungurwe.
zviratidzo	1. inoshandiswa pakukurumidzira hypotension yekukurumidzira kwehutano hwehutano, zvakadai sehutano hwehutano, hypertensive encephalopathy, malignant hypertension, paroxysmal hypertension isati yasvika uye mushure mekuvhiyiwa kwe pheochromocytoma, uye inogonawo kushandiswa pakudzora hypotension panguva yekuvhiya anesthesia. 2. Nokuda kwekushaya simba kwemoyo, kusanganisira acute pulmonary edema. Inoshandiswawo kune acute heart failure in acute myocardial infarction kana kana valve (mitral kana aortic valve) isina kuvharwa.
pharmacokinetics	svika panhongonya yeropa nekukurumidza mushure mekudonha mutsinga, uye nhanho yaro inoenderana nedosi. Ichi chigadzirwa chinogadziriswa nemasero matsvuku eropa mu cyanide, cyanide muchiropa inogadziriswa mu thiocyanate, uye metabolite haina basa re vasodilating; cyanide inogonawo kutora chikamu mune metabolism yevhitamini B12. Ichi chigadzirwa chinoshanda nekukurumidza mushure mekutonga uye chinosvika panhongonya yechiito, uye chinochengetedza 1 ~ 10 maminetsi mushure mekupinda mutsinga kudonha kwakamira. Hafu yehupenyu hwevarwere vane hutano hwemazuva ose ndeyemazuva manomwe (akayerwa ne thiocyanate), yakareba kana renal basa risina kunaka kana kuti sodium yeropa yakanyanya kuderera, uye inobudiswa neitsvo.
A synthetic process yekugadzirira	sodium nitroprusside, kusanganisira matanho anotevera: 1) Kugadzira mhangura nitroso ferrocyanide: kuwedzera huwandu hwakakodzera hwemvura yakacheneswa kunyungudutsa potassium nitroso-ferricyanide mu crystallization tank, kupisa kusvika 70-80 ℃ kuinyungudutsa zvachose, uye zvishoma nezvishoma kuwedzera copper sulfate pentahydrate. aqueous solution inodonha, mushure mekuita ichichengetwa ichidziya kwemaminitsi makumi matatu, centrifuge, iyo centrifuged sefa keke (copper nitroso ferricyanide) yakaiswa mucrystallization tank. 2) Synthetic sodium nitroprusside (sodium nitronitroferricyanide): Gadzirira saturated sodium bicarbonate aqueous solution maererano nehuwandu hwekudya, uye zvishoma nezvishoma uidonhedze mu nitroso ferricyanide pa 30-60 degrees C. Mushure mekuita, centrifuge, unganidza filtrate uye lotion. 3) Concentration uye crystallization: Iyo yakaunganidzwa filtrate uye lotion inopombwa kune vacuum yevasungwa tangi, uye glacial acetic asidhi inowedzerwa zvishoma nezvishoma inodonha kusvika pasina mabhubhu anogadzirwa. Batidza pombi yevacuum uye kupisa kusvika ku40-60 madhigirii C, tanga kutarisisa, tarisa kune huwandu hukuru hwemakristasi kunaya, vhara vharafu yemhepo, vacuum valve kugadzirira crystallization. 4) Kuomeswa kweCentrifugal: mushure mekristallisation, iyo supernatant inobviswa, makristasi anomutswa zvakaenzana uye akaiswa centrifuged, keke yekusefa inoiswa mundiro yesimbi isina tsvina, uye chigadzirwa chinowanikwa nekuomeswa kwevacuum.
biological chiitiko	Sodium Nitroprusside ivasodilator ine simba inoshanda nekungoerekana yaburitsa NO muropa.
Target	Value
Shandisa	Inoshandiswa seagent yekugadzirisa aldehydes, ketoni, sulfides, zinc, sulfur dioxide, nezvimwewo. Inoshandiswa seagent yekugadzika kwe aldehydes, acetone, sulfur dioxide, zinc, Alkali metals, sulfides, nezvimwe. Vasodilators. Kuongororwa kwe aldehydes uye ketones, zinc, sulfur dioxide uye alkali metal sulfides. Chromatic analysis, weti bvunzo.